Immediately attain sections as thin or thick as your application demands, without the need of worrying about losing or distorting important tissue samples.

Megatome is usually a vibrating microtome designed to segment a broad variety of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With significant blade vibrating frequency and minimized blade deflection, Megatome permits higher-throughput tissue sectioning with uniform surface area profile, along with nominal tissue injury and data reduction.

Antibodies may possibly just take months to diffuse by way of just a few millimeters of tissue, which has a steep labeling gradient from surface to core.

Megatome is designed for accuracy: the blade vibrates at the next frequency and bigger amplitude range than other microtomes, and encompasses a special deflection Handle mechanism.

SE works by using a rotational electrical discipline to disperse very electromobile molecules (like antibodies or surfactant micelles) all through a porous sample without harming electrically billed structures in the tissue. This permits 2-4 working day clearing of intact organs,

Our preformulated EasyIndex solution raises and homogenize the refractive index of delipidated tissue samples, rendering them thoroughly clear. This enables light-weight penetration in the sample and assures the acquisition of higher-resolution, in-aim impression knowledge.

Megatome is actually a novel microtome that allows for prime-precision sectioning of a wide range of tissue samples – from organoids, to arrays of animal organs, to intact human Mind hemispheres – with negligible tissue damage and knowledge decline.

eFLASH is actually a rapid tissue labeling strategy that allows for uniform total-organ staining in 20 rounds of labeling.

The SmartSPIM light-weight sheet microscope megatomi.com gives unparalleled resolution and acquisition velocity during intact tissue volumes, while its modular layout allows you to up grade and customise person factors.

Docset creation requires at minimum two options: the name from the docset and the location from the Javadoc information to include within the docset.

This tends to make a docset named Sample in The present directory. Docset creation can be customized with optional arguments:

Defend avoids the variability of hydrogel embedding and the knowledge loss from PFA preservation, preserving specimens for many rounds of processing.

--displayName: Will established the title as shown in Sprint. That is handy for those who develop a docset with name SampleProject but display identify Sample Undertaking instead. This environment will default to the value of --identify if omitted.

This plugin applies the java plugin to the undertaking It truly is operate under. Which means inside of a multi-module project, a best stage endeavor named javadoc cannot be developed to combination the